Atrial fibrillation and vascular dementia: an integrative literature review

Authors

  • Caroline Melo de Sousa Centro Universitário de Patos - UNIFIP
  • Milena Nunes Alves Sousa
  • Fabrício Kleber de Lucena Carvalho

DOI:

https://doi.org/10.56083/RCV2N3-035

Keywords:

Atrial fibrillation; Vascular Dementia; Stroke; Prognosis; Quality of life.

Abstract

Atrial fibrillation is a subtype of cardiac arrhythmia, being the most common. It corresponds to a disorganization of the electrical activity of the heart's atria, which lose their ability to contract, resulting in tachycardia. Vascular dementia, on the other hand, corresponds to a decrease in the ability to perform cognitive functions due to the occurrence of cerebral microinfarctions. The aim of this study was to analyze the correlation between atrial fibrillation and vascular dementia, in the presence or absence of stroke. In this integrative review, a bibliographic search was carried out in the Virtual Health Library, National Library of Medicine and Scientific Electronic Library Online. The Health Sciences Descriptors Atrial Fibrillation, Vascular Dementia, Stroke, Prognosis and Quality of Life were used. Thus, it was found that atrial fibrillation predisposes to the development of Cerebral Vascular Accident, since the blood trapped in the atria due to the loss of its ability to contract can lead to the formation of small clots, which when transported by the bloodstream to the brain may cause the aforementioned microinfarcts. Therefore, there may be a progressive loss of cognition compatible with vascular dementia itself, worsening prognosis and reduced quality of life.

References

ALTURKI, Ahmed et al. The Role of Cardiovascular and Metabolic Comorbidities in the Link between Atrial Fibrillation and Cognitive Impairment: an appraisal of current scientific evidence. Medicina, v. 55, n. 12, p. 767, 30 nov. 2019 DOI: https://doi.org/10.3390/medicina55120767

CAMM, John et al. Does ablation of atrial fibrillation reduce the likelihood of dementia? A step closer but not yet there. European Heart Journal, v. 41, n. 47, p. 4494-4496, 11 nov. 2020 DOI: https://doi.org/10.1093/eurheartj/ehaa843

CHANG, Ya-Ting et al. Revealing the Influences of Sex Hormones and Sex Differences in Atrial Fibrillation and Vascular Cognitive Impairment. International Journal of Molecular Sciences, v. 22, n. 16, p. 8776, 16 ago. 2021 DOI: https://doi.org/10.3390/ijms22168776

CHINTA, Viswanatha et al. Atrial Fibrillation and Deterioration in Cognitive Function. Current Problems In Cardiology, v. 44, n. 11, p. 100386, nov. 2019 DOI: https://doi.org/10.1016/j.cpcardiol.2018.07.001

CHUNG, Mina et al. Lifestyle and Risk Factor Modification for Reduction of Atrial Fibrillation: A Scientific Statement From the American Heart Association. Circulation, v. 141, n. 16, p. 750-772, 21 abr. 2020 DOI: https://doi.org/10.1161/CIR.0000000000000748

CINTRA, Fátima et al. Fibrilação Atrial (Parte 1): fisiopatologia, fatores de risco e bases terapêuticas. Arquivos Brasileiros de Cardiologia, v. 116, n. 1, p. 129-139, jan. 2021 DOI: https://doi.org/10.36660/abc.20200485

COSTA, Guilherme. Fibrilação Atrial. Sociedade Beneficente Israelita Brasileira, v. 18, n. 1, p.1-5, out. 2018

DAGRES, Nikolaos et al. Guidelines for the diagnosis and management of atrial fibrillantion developed in collaboration with the European Association of Cardio-Thoracic Surgery. Scientific Document Group’s, v. 20, n.19, p. 1399–1421, ago. 2020

CRUZ JÚNIOR, Francisco et al. Fibrilação atrial, tratamento antitrombótico e envelhecimento cognitivo: Um estudo de base populacional. Revista Norte Nordeste de Cardiologia, v. 8, n. 4, p. 5-8, mar. 2018

FERNANDES NETO, José et al. Fibrilação Atrial. Revista Qualidade HC, , v. 20, n. 13, p. 1-7, jul. 2018

FIELD, Thalia et al. Incident Atrial Fibrillation, Dementia and the Role of Anticoagulation: a population-based cohort study. Thrombosis And Haemostasis, v. 119, n. 6, p. 981-991, mar. 2019 DOI: https://doi.org/10.1055/s-0039-1683429

FORMIGA, Francesca et al. Atrial fibrillation and cognitive impairment: some answers but many questions. Revista Española de Cardiología (English Edition), v. 73, n. 11, p. 869-870, nov. 2020 DOI: https://doi.org/10.1016/j.rec.2020.03.019

FRIBER, Leif et al. Less dementia and stroke in low-risk patients with atrial fibrillation taking oral anticoagulation. Europa Heart Journal, v. 40, n. 104, p. 2327–2335, set. 2019 DOI: https://doi.org/10.1093/eurheartj/ehz304

MEYRE, Pascal et al. Risk of Hospital Admissions in Patients With Atrial Fibrillation: A Systematic Review and Meta-analysis. Canadian Journal Cardiology, v. 35, n. 10, p. 1332-1343, oct. 2019 DOI: https://doi.org/10.1016/j.cjca.2019.05.024

HACHUL, Denise. Fibrilação atrial causa avc/derrame. Sociedade Brasileira de Arritmias Cardíacas, v. 37, n. 23, p. 1-7, mai. 2021

IHARA, Masafumi et al. Linking atrial fibrillation with Alzheimer’s disease: epidemiological, pathological, and mechanistic evidence. Journal Alzheimers Dis, v. 62, n. 1, p 61-72, jan. 2018 DOI: https://doi.org/10.3233/JAD-170970

KIM, Daehoon et al. Blood Pressure Control and Dementia Risk in Midlife Patients With Atrial Fibrillation. Hypertension, v. 75, n. 5, p. 1296-1304, mai. 2020 DOI: https://doi.org/10.1161/HYPERTENSIONAHA.119.14388

KIM, Dongmin et al. Risk of dementia in stroke-free patients diagnosed with atrial fibrillation: data from a population-based cohort. European Heart Journal, v. 40, n. 28, p. 2313-2323, jun. 2019 DOI: https://doi.org/10.1093/eurheartj/ehz386

KRAWCZYK, Michal et al. Atrial fibrillation diagnosed after stroke and dementia risk: cohort study of first-ever ischaemic stroke patients aged 65 or older. Ep Europace, v. 21, n. 12, p. 1793-1801, set. 2019 DOI: https://doi.org/10.1093/europace/euz237

KÜHNE, Michael et al. The heart-brain connection: further establishing the relationship between atrial fibrillation and dementia? European Heart Journal, v. 40, n. 28, p. 2324-2326, jul. 2019 DOI: https://doi.org/10.1093/eurheartj/ehz483

LIN, Mingjie et al. A systematic review and meta‐analysis to determine the effect of oral anticoagulants on incidence of dementia in patients with atrial fibrillation. International Journal of Clinical Practice, v. 75, n. 10, p. 1-9, 2 mai. 2021 DOI: https://doi.org/10.1111/ijcp.14269

MITCHELL, Brent. Fibrilação Atrial. Libin Cardiovascular Institute of Alberta, University of Calgary, v.7, n. 29, p. 1-4, jul. 2019

MAILHOT, Tanya et al. Frailty, Cognitive Impairment, and Anticoagulation Among Older Adults with Nonvalvular Atrial Fibrillation. Clinical Investigation, v. 0, n. 1, p. 1-9, mar. 2020

MAILHOT, Tanya et al. Frailty, Cognitive Impairment, and Anticoagulation Among Older Adults with Nonvalvular Atrial Fibrillation. Journal of the American Geriatrics Society, v. 68, n. 12, p. 2778-2786, ago. 2020 DOI: https://doi.org/10.1111/jgs.16756

MONGKHON, Pajaree et al. Oral anticoagulant and reduced risk of dementia in patients with atrial fibrillation: a population-based cohort study. Heart Rhythm, v. 17, n. 5, p. 706-713, mai. 2020 DOI: https://doi.org/10.1016/j.hrthm.2020.01.007

NAH, Min-Ah et al. Association Between Atrial Fibrillation and the Risk of Dementia in the Korean Elderly: a 10-year nationwide cohort study. Journal of Preventive Medicine And Public Health, v. 53, n. 1, p. 56-63, jan. 2020 DOI: https://doi.org/10.3961/jpmph.19.117

PAZ, Rafael et al. Impact of Anticoagulation in Patients With Dementia and Atrial Fibrillation. Revista Española de Cardiología (English Edition), v. 73, n. 11, p. 877-884, nov. 2020. DOI: https://doi.org/10.1016/j.rec.2019.10.025

PINHEIRO, Chloé. Pessoas com fibrilação atrial têm o dobro de risco de demência. Revista Veja Saúde, v. 25, n.12, p. 4-6, jul. 2019

RUSSO, Vincenzo et al. Stroke, Dementia, and Atrial Fibrillation: from pathophysiologic association to pharmacological implications. Medicina, v. 56, n. 5, p. 227, mai. 2020 DOI: https://doi.org/10.3390/medicina56050227

SHAO, Iris et al. Association of Atrial Fibrillation With White Matter Disease. Stroke, v. 50, n. 4, p. 989-991, abr. 2019. DOI: https://doi.org/10.1161/STROKEAHA.118.023386

SHAMLOO, Alireza et al. Atrial Fibrillation and Cognitive Impairment: new insights and future directions. Heart, Lung And Circulation, v. 29, n. 1, p. 69-85, jan. 2020. DOI: https://doi.org/10.1016/j.hlc.2019.05.185

VESCOVO, J. Demência Vascular. Associação Alzheimer Portugal, v. 16, n. 2, p-3-6, set. 2019

WÄNDELL, Per et al. Association Between Relevant Co-Morbidities and Dementia With Atrial Fibrillation–A National Study. Archives of Medical Research, v. 50, n. 2, p. 29-35, fev. 2019. DOI: https://doi.org/10.1016/j.arcmed.2019.05.007

Published

2022-06-01

How to Cite

Sousa, C. M. de ., Sousa, M. N. A. ., & Carvalho, F. K. de L. . (2022). Atrial fibrillation and vascular dementia: an integrative literature review. Revista Contemporânea, 2(3), 739–759. https://doi.org/10.56083/RCV2N3-035

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Articles